Antihypertensive activity of the non-peptide angiotensin II receptor antagonist, SK&F 108566, in rats and dogs
โ Scribed by David P. Brooks; Todd A. Fredrickson; Joseph Weinstock; Robert R. Ruffolo; Richard M. Edwards; Miklos Gellai
- Book ID
- 112274719
- Publisher
- Springer-Verlag
- Year
- 1992
- Tongue
- English
- Weight
- 614 KB
- Volume
- 345
- Category
- Article
- ISSN
- 0028-1298
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
DuP 532, 2-propy1-4-pentafluoroethyl-l-[ [2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methylJ imidazole-5-carboxylic acid, is an orally active, non-peptide angiotensin I1 (AII) receptor antagonist. DuP 532 is more potent and longer acting than losartan, another A11 receptor antagonist currently undergoing ph
166 is an orally active, non-peptide angiotensin II (AII) receptor antagonist developed for the treatment of hypertension and congestive heart failure (CHF). In this study, the intravenous (iv) and oral (po) single dose pharmacokinetics (PK), oral multiple dose PK and P450-mediated metabolism of 16