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Antihypertensive activity of 1-dimethylphosphinylmethyl-4-arylpiperazines

โœ Scribed by Glamkowski, Edward J.; Strupczewski, Joseph; Wolf, Erhard; Woodward, David L.

Book ID
126120520
Publisher
American Chemical Society
Year
1974
Tongue
English
Weight
252 KB
Volume
17
Category
Article
ISSN
0022-2623

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Conformational analysis of 1-arylpiperaz
Conformational analysis of 1-arylpiperazines and 4-arylpiperidines
โœ Gerard D. H. Dijkstra ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 741 KB

## Abstract A conformational analysis of 1โ€arylpiperazines and 4โ€arylpiperidines is presented using molecularโ€mechanics and semiโ€empirical calculations. It has been found that electronic effects of substituents on the aryl ring determine the conformational behaviour of 1โ€arylpiperazines. Steric eff