Antihypertensive 1-acyl-4-[2-(1,4-benzodioxan-2-yl)-2-hydroxyethylamino]piperidines
✍ Scribed by Joan M. Caroon; Robin D. Clark; David B. Repke; Arthur F. Kluge; Arthur M. Strosberg; Roger L. Whiting; Marlys D. Okada; Linda R. Hedley; Donna van Antwerp; Christine M. Brown
- Book ID
- 102407791
- Publisher
- John Wiley and Sons
- Year
- 1987
- Tongue
- English
- Weight
- 279 KB
- Volume
- 76
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
In the title compound, C 16 H 28 ClN 5 , the piperidine ring has a classical chair conformation. In the crystal structure, weak intermolecular N-HÁ Á ÁN hydrogen bonds link two molecules, related by a twofold axis of symmetry, into dimers.
The molecule of the title compound, C 16 H 17 FN 4 OS 2 , is built up around a chiral C atom, and exists in a propeller-like arrangement. The structure is stablized by van der Waals interactions.