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Antiherpetic Flavones from the Heartwood of Artocarpus gomezianus

✍ Scribed by Kittisak Likhitwitayawuid; Saowalak Chaiwiriya; Boonchoo Sritularak; Vimolmas Lipipun


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
72 KB
Volume
3
Category
Article
ISSN
1612-1872

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✦ Synopsis


Abstract

The heartwood of Artocarpus gomezianus was investigated for anti‐herpetic principles. During the course of the separation, a new compound, artogomezianone (1), was isolated, along with the known compounds cycloartocarpin (2), isocyclomorusin (3), artocarpin (4), norcycloartocarpin (5), norartocarpetin (6), and oxyresveratrol (7). Evaluation of these isolates for inhibitory effects against herpes simplex virus (HSV) typesβ€…1 and 2 was carried out using the inactivation method. Compounds 2, 3, 6 and 7 showed moderate activities against both types of HSV, while 1, 4 and 5 were basically inactive (Tableβ€…2).


πŸ“œ SIMILAR VOLUMES


Flavonoid pigments of the heartwood of A
✍ K.G. Dave; S.A. Telang; K. Venkataraman πŸ“‚ Article πŸ“… 1962 πŸ› Elsevier Science 🌐 French βš– 258 KB

MORIN (3, 5, 7, 2', .!+I-pentahydroxyflavone) and the colourless cyanomaclurin, to which Appel and Robinson1 assigned the structure of a cyclic hemiketal of 5, 7, 2', ,!+I-tetrahydroxy-3-ketoflavan, were isolated by Perkin and Cope 2,3 from the heartwood of Artocarous inteqrifolia. We have recently