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Antihelicase action of CI-958, a new drug for prostate cancer

✍ Scribed by Lapman Lun; Pei-Ming Sun; Charles M. Trubey; Nicholas R. Bachur

Book ID
105994406
Publisher
Springer
Year
1998
Tongue
English
Weight
247 KB
Volume
42
Category
Article
ISSN
0344-5704

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## Abstract The emergence of mutations in the androgen receptor (__AR__) gene is a recurrent event during progression of prostate cancer (PCa) on androgen ablation therapy. In this study, we show that nonsense mutations that lead to carboxyl‐terminal end truncated ARs are found at high frequency in