Antigenic structure of the herpes simplex virus type 1 glycoprotein C: Demonstration of a linear epitope situated in an environment of highly conformation-dependent epitopes

Influence of sequential oligopeptide car

Influence of sequential oligopeptide carriers on the bioactive structure of conjugated epitopes: Comparative study of the conformation of a Herpes simplex virus glycoprotein gD-1 epitope in the free and conjugated form, and protein “built-in” crystal structure

✍ Dimitrios Krikorian; Athanassios Stavrakoudis; Nikolaos Biris; Constantinos Saka 📂 Article 📅 2006 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 642 KB

## Abstract Synthetic carriers play an important role in immunogen presentation, due to their ability of inducing improved and specific responses to conjugated epitopes. Their influence on the bioactive conformation of the epitope, though admittedly crucial for relevant in vitro and in vivo applica