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Antigenic properties of human and animal bloodstains studied by enzyme-linked immunosorbent assay (ELISA) using various antisera against specific plasma proteins

✍ Scribed by Tsutsumi, H. ;Htay, H.H. ;Sato, K. ;Katsumata, Y.


Publisher
Springer-Verlag
Year
1987
Tongue
English
Weight
382 KB
Volume
99
Category
Article
ISSN
1437-1596

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✦ Synopsis


Antigenic properties of bloodstains of human and non-human primates as well as other animal bloodstains were investigated by the inhibition ELISA using commercially available anti-human albumin (Alb), a2macroglobulin (a2-M), fibrinogen, transferrin, and immunoglobulin G. In general, chimpanzee bloodstains showed strong cross-reactions with these antisera, and the extent of the cross-reactions of other animal bloodstains decreased largely with the phylogenic order, i.e., agile gibbon (ape), Old World monkeys (Japanese monkey and hamadryas baboon), New World monkeys (night monkey and tufted capuchin monkey), prosimians (grand galago and ring-tailed lemur) and other animals (rat, cattle, swine, goat, dog, cat, and chicken). Among these antisera, anti-human aa-M showed the weakest cross-reaction with chimpanzee bloodstains, and anti-human Alb showed next.