The immune system has evolved complex mechanisms for the recognition and elimination of pathogens. CD4/ helper T lymphocytes play a central role in orchestrating immune responses and their activation is carefully regulated. These cells selectively recognize short peptide antigens stably associated w
Antigenic peptide binding by class I and class II histocompatibility proteins
โ Scribed by Lawrence J Stern; Don C Wiley
- Book ID
- 114328630
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 672 KB
- Volume
- 2
- Category
- Article
- ISSN
- 0969-2126
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## Abstract The activation of helper T cells by peptides bound to proteins of the class II Major Histocompatibility Complex (MHC II) is pivotal to the initiation of an immune response. The primary functional requirement imposed on MHC II proteins is the ability to efficiently bind thousands of diff
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