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Antigen-specific T cell trafficking into the central nervous system

โœ Scribed by Zhu Qing; Diane Sewell; Matyas Sandor; Zsuzsa Fabry

Book ID
114139044
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
701 KB
Volume
105
Category
Article
ISSN
0165-5728

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The entry of T-lymphocytes into the parenchyma of the central nervous system is a critical early feature in the pathogenesis of many experimental and spontaneously occurring immune-mediated illnesses. The physiological mechanisms controlling this entry have not been elucidated. This study reports th