𝔖 Bobbio Scriptorium
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Antigen-specific suppressor T cell factors

✍ Scribed by M. J. Taussig

Publisher
Springer-Verlag
Year
1980
Tongue
English
Weight
871 KB
Volume
9
Category
Article
ISSN
0340-7004

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✦ Synopsis

Antigen-specific suppressor factors are products of suppressor T cells which possess specificity for the antigens by which they are induced. They probably play a significant role in immunoregulation. They are not classic immunoglobulins, and they carry determinants of the major histocompatibility complex. This review discusses the literature on their production, structure, genetic restriction in activity and mechanism of action.

while lacking most of the characteristics of the more familiar antigen-recognition system, namely antibodies, and (b) their relationship to the major histocompatibility complex. Antigen-specific suppressor factors have been described in connection with many different antigens, including proteins, haptens, synthetic polypeptides, red cells and tumour cells. Table 2 provides a comprehensive guide to the literature up to the time of writing (May, 1980).

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