Antigen-reactive cells in the spleen of mice with methylcholanthrene-induced sarcoma
β Scribed by L. V. Yakimenko; Yu. A. Umanskii
- Publisher
- Springer US
- Year
- 1974
- Tongue
- English
- Weight
- 276 KB
- Volume
- 77
- Category
- Article
- ISSN
- 0007-4888
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This study was designed to investigate the nature of lymphocyte reactivity to soluble tumor antigens with respect to the kinetics of the reactivity, the responding cell type, and the role of accessory cells, within a syngeneic system. BALB/c mice were inoculated with 1 X 10(6) viable cells of syngen
## Abstract The characteristics of tumor antigens of the transplantation type, TATA, were studied in a series of methylcholanthreneβinduced sarcomas in pedigreed BALB/cAN mice. Each of the six sarcomas exhibited unique TATA when assayed for tumor rejection in syngeneic hosts. In three instances, ho
## Abstract The tumorigenic EPO clonal cell line, derived from a methylcholanthreneβinduced murine sarcoma, was exposed to increasing concentrations of actinomycin D and gave rise to a subline, resistant to 0.02 ΞΌg of actinomycin D per ml of medium, which was designated EPO/ADj. Drug resistance was