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Antigen-presenting cells recruited by Brugia malayi induce Th2 differentiation of naïve CD4+ T cells

✍ Scribed by P'ng Loke; Andrew S. MacDonald; Judith E. Allen


Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
187 KB
Volume
30
Category
Article
ISSN
0014-2980

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The role of TGF-g 1 in the regulation of T cell responses has been perplexing, possibly because it is dependent on the type of T cell being regulated and its cytokine microenvironment. In the present study, we demonstrate that TGF-g 1 has a profound inhibitory effect on naive CD4 + T cell undergoing