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Antigen presentation by keratinocytes induces tolerance in human T cells

✍ Scribed by Vineeta Bal; Angus McIndoe; Graeme Denton; David Hudson; Giovanna Lombardi; Jonathan Lamb; Robert Lechler


Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
562 KB
Volume
20
Category
Article
ISSN
0014-2980

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Professional antigen-presenting cells (APC), e.g. dendritic cells, express immuno-proteasome components and process proteins for MHC presentation differently from non-immune cells. Thus, they induce reactivities against sets of peptides that do not overlap with those generated by non-professional AP