Antigen persistence is required for somatic mutation and affinity maturation of immunoglobulin

Role of membrane receptors in the induct

Role of membrane receptors in the induction of an in vitro secondary anti-hapten response II. Antigen-immunoglobulin receptor interaction is not required for B memory cell proliferation

✍ S. Cammisuli; Claudia Henry 📂 Article 📅 1978 🏛 John Wiley and Sons 🌐 English ⚖ 533 KB

## Abstract In this study it has been investigated whether the interaction of antigen and B cell surface immunoglobulin (sIg) is required for full clonal expansion of memory B cells specific for the hapten, p‐azophenyl‐lactoside (lac). Cultures of lac‐primed B cells and keyhole limpet hemocyanin (K