## Abstract ## Background Tumors develop mechanisms to escape recognition by the immune system. It has recently been demonstrated that tumors cause apoptotic death of key immune cells, including the major antigen‐presenting cells, dendritic cells (DC). Elimination of DC from the tumor environment
✦ LIBER ✦
Antigen loading of DCs with irradiated apoptotic tumor cells induces improved anti-tumor immunity compared to other approaches
✍ Scribed by Terry J. Fry; Jessica L. Shand; Matthew Milliron; Sarah K. Tasian; Crystal L. Mackall
- Book ID
- 105967556
- Publisher
- Springer-Verlag
- Year
- 2009
- Tongue
- English
- Weight
- 523 KB
- Volume
- 58
- Category
- Article
- ISSN
- 0340-7004
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## Abstract We have previously developed 3 monoclonal anti‐idiotypic antibodies (Ab2) of LOU rat origin directed against the binding site of the murine monoclonal IgM LAM8, which recognizes the small‐cell lung carcinoma (SCLC)‐associated sialoglycoprotein antigen sGP~90–135~. The aim of this study