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Antigen-independent suppression of the IgE immune response to bee venom phospholipase A2 by maternally derived monoclonal IgG antibodies

โœ Scribed by Marcus Seeger; Hermann-J. Thierse; Hans Lange; Lee Shaw; Hinrich Hansen; Hilmar Lemke

Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
122 KB
Volume
28
Category
Article
ISSN
0014-2980

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Comparison of the antibody response to bee venom phospholipase A2 induced by natural exposure in humans or by immunization in mice
โœ Theres Schneider; Thomas Dudler; Robert R. Annand; Michael H. Gelb; Te P. King; ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 214 KB ๐Ÿ‘ 2 views

Two human and twelve murine monoclonal antibodies directed against the main bee venom allergen phospholipase A 2 (PLA) were evaluated for their fine specificity of binding to antigen and their ability to inhibit the enzymatic activity of the antigen. Antibodies were induced by natural exposure of be