This study examined whether mesenchymal stem cells (MSCs), which are stem cells originated from embryonic mesoderm, are able to differentiate into functional hepatocyte-like cells in vitro. MSCs were isolated from human bone marrow and umbilical cord blood, and the surface phenotype and the mesoderm
Antigen expression profile and differentiation potential of mesenchymal stem cells and hepatic stellate cells from adult human liver
✍ Scribed by F. Colombo; L. Porretti; A. Cattaneo; A. D’Ambrosio; G. Rossi; B. Foglieni; S. Candelaresi; G. Svegliati-Baroni; D. Prati
- Book ID
- 119229130
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 56 KB
- Volume
- 40
- Category
- Article
- ISSN
- 1590-8658
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## Abstract Differentiation of stem cells is tightly regulated by the microenvironment which is mainly composed of nonparenchymal cells. Herein, we investigated effect of hepatic stellate cells (HSCs) in different states on mesenchymal stem cells (MSCs) differentiation. Rat HSCs were isolated and s
## Abstract ## Background Mesenchymal stem cells (MSCs) have drawn considerable attention as vehicles for cell‐ or gene‐based therapies, yet various problems still exist for current gene delivery vectors. On the other hand, baculovirus has emerged as a novel gene therapy vector, but its transducti