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Antigen-Driven T Cell Expansion: Affinity Rules

โœ Scribed by Jonathan D. Ashwell


Book ID
116570374
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
39 KB
Volume
21
Category
Article
ISSN
1074-7613

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โœ CHRISTOPHE FRASER; NEIL M. FERGUSON; FRANK DE WOLF; AZRA C. GHANI; GEOFF P. GARN ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 272 KB

A mathematical model is developed to characterize the distribution of cell turnover rates within a population of T lymphocytes. Previous models of T-cell dynamics have assumed a constant uniform turnover rate; here we consider turnover in a cell pool subject to clonal proliferation in response to di