Antifungal prophylaxis in liver transplant recipients: a randomized placebo-controlled study
✍ Scribed by Gianni Biancofiore,Maria L. Bindi,Rubia Baldassarri…
- Book ID
- 113019951
- Publisher
- Springer
- Year
- 2002
- Tongue
- English
- Weight
- 89 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0934-0874
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Although the overall incidence of fungal infections in liver transplant recipients has declined, these infections still contribute significantly to the morbidity and mortality of patients with risk factors for infection. Although antifungal prophylaxis has been widely studied and practiced, no conse
UNOS status 4 (life support in ICU) 146 6.3 (2.4-16.7) George 1997 ( 14 ) Donor CMV þ/recipient -146 4.8 (2.0-11.8) George 1997 ( 14 ) UNOS class I (life support in ICU) 172 3.5 (1.7-7.0) Winston 1999 ( 23 ) Fungal colonization at baseline 172 2.3 (1.2-4.3) Winston 1999 ( 23 ) Pretransplant SCr 3 mg
Background: Among persons who receive solid organ transplants, liver transplant recipients have the highest incidence of invasive fungal infection; however, no antifungal prophylaxis has been proven to be effective. ## Objective : To evaluate the efficacy and safety of prophylactic fluconazole in