Antifungal properties of pristimerin and celastrol isolated from Celastrus hypoleucus

✍ Scribed by Du-Qiang Luo; Hong Wang; Xuan Tian; Hong-Jun Shao; Ji-Kai Liu

• Book ID: 105359590
• Publisher: John Wiley and Sons
• Year: 2004
• Tongue: English
• Weight: 135 KB
• Volume: 61
• Category: Article
• ISSN: 1526-498X
• DOI: 10.1002/ps.953

✦ Synopsis

Abstract

Pristimerin and celastrol isolated from the roots of Celastrus hypoleucus (Oliv) Warb f argutior Loes exhibited inhibitory effects against diverse phytopathogenic fungi. Pristimerin and celastrol were found to inhibit the mycelial growth of Rhizoctonia solani Kühn and Glomerella cingulata (Stonem) Spauld & Schrenk in vitro by 83.6 and 62.6%, respectively, at 10 µg ml^−1^. Pristimerin showed good preventive effect (96.7% at 100 µg ml^−1^) and curative effect (66.5% at 100 µg ml^−1^) against wheat powdery mildew in vivo. For celastrol, the preventive and curative effects against wheat powdery mildew were 80.5 and 45.4%, respectively, at 100 µg ml^−1^. Copyright © 2004 Society of Chemical Industry