Antifungal activity of some Bignoniaceae found in Malaysia

✍ Scribed by Rasadah Mat Ali; Peter J. Houghton; T. S. Hoo

• Publisher: John Wiley and Sons
• Year: 1998
• Tongue: English
• Weight: 112 KB
• Volume: 12
• Category: Article
• ISSN: 0951-418X
• DOI: 10.1002/(sici)1099-1573(199808)12:5<331::aid-ptr305>3.0.co;2-w

✦ Synopsis

The dichloromethane extracts of Tabebuia chrysantha, Oroxylum indicum, Fernandoa adenophylla and Jacaranda filicifolia display antifungal activity against dermatophytes and wood rot fungi. The activity is probably due mainly to lapachol and b-lapachone which were shown to be present in these plant extracts. Microscopical study has shown that these extracts inhibit the development of mycelium and conidia in the filamentous fungi.