Antifungal activity of dihydrodioscorine extracted from a wild variety of Dioscorea bulbifera L

✍ Scribed by Adetoun Adeleye; Dr. T. Ikotun

• Publisher: John Wiley and Sons
• Year: 1989
• Tongue: English
• Weight: 206 KB
• Volume: 29
• Category: Article
• ISSN: 0233-111X
• DOI: 10.1002/jobm.3620290504

✦ Synopsis

The bulbils and tubers of a wild variety of Dioscorea bulbifera L. contained an alkaloid, dihydrodioscorine. When crystallized in its hydrochloride form and incorporated into potato dextrose agar at a final concentration of O.l?<, it was found to slow down the rate of growth of five plant pathogenic fungi namely: Sclerotiurn rolfsii, Curvulariu lunata, Fusarium nionilifortne, Macrophomina phaseolina and Botryodiplodiu theobromae. Also sclerotia formation in S. rolfsii was delayed and the number was reduced. Conidia formation in C. lunata and F. rnoniliforme was also delayed and reduced but pycnidia formation in M . phaseolina and B. theobromae was not affected. There was no significant difference between the rate of growth of the fungi on PDA incorporated with 0.01 "I, final concentration of dihydrodioscorine and on control plates. Abbreviations: PDA = potato dextrose agar, D.D. = dihydrodioscorine dihydrochloride