Antifibrogenic activity of interferon alpha in chronic hepatitis C
β Scribed by Takeaki Suou
- Publisher
- Springer Japan
- Year
- 1999
- Tongue
- English
- Weight
- 43 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0944-1174
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## Abstract The effectiveness of a daily continuous infusion of interferonβalpha was evaluated in 12 patients (10 males, 2 females; mean age of 33 years, range 19β62) with biopsyβproven chronic active hepatitis C. Nine million units (MU) of recombinant interferonβalpha 2A (rIFNβΞ± 2A) were administe
Interferon (IFN) demonstrates antiviral activity by binding to receptors on the cell surface. Expression of the IFN receptor in hepatocytes may be directly associated with a hepatitis C virus (HCV) infection and the response to IFN therapy. A competitive PCR method was developed to measure IFN alpha