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Antiestrogenic and antitumor properties of the new triphenylethylene derivative toremifene in the rat

✍ Scribed by E. Di Salle; T. Zaccheo; G. Ornati

Book ID
116007760
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
419 KB
Volume
36
Category
Article
ISSN
0022-4731

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Pharmacokinetics of the novel antiestrog
Pharmacokinetics of the novel antiestrogenic agent toremifene in subjects with altered liver and kidney function
✍ Anttila, Markku; Laakso, Sirpa; NylÀnden, Pirkko; Sotaniemi, Eero A. πŸ“‚ Article πŸ“… 1995 πŸ› Nature Publishing Group 🌐 English βš– 840 KB

O&ect&es: The pharmacokinetics of toremifene was investigated in an open study with four parallel groups of 10 subjects each. Subjects with impaired liver function (biopsy-proven liver disease), activated liver function (drug-induced), and impaired kidney function were compared with normal subjects.