Antiestrogenic activity of DP-TAT-59, an active metabolite of TAT-59 against human breast cancer

Antitumor effect of triphenylethylene de

Antitumor effect of triphenylethylene derivative (TAT-59) against human breast carcinoma xenografts in nude mice

✍ Dr. Jun-Ichi Koh; Tetsuro Kubota; Fumiki Asanuma; Yoshinori Yamada; Eiji Kawamur 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 466 KB 👁 1 views

## Abstract The antitumor activity of a newly synthesized triphenylethylene derivative {(E)‐4‐[1‐4‐[2‐(dimethylamino)ethoxy‐phenyl]‐2‐(4‐isopropyl)phenyl‐1‐butenyl] phenyl monophosphate} (TAT‐59) was investigated against human breast carcinoma xenografts in nude mice with reference to the changes o