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Antiestrogen resistance in breast cancer and the role of estrogen receptor signaling

โœ Scribed by Clarke, Robert; Liu, Minetta C; Bouker, Kerrie B; Gu, Zhiping; Lee, Richard Y; Zhu, Yuelin; Skaar, Todd C; Gomez, Bianca; O'Brien, Kerry; Wang, Yue


Book ID
110068022
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
310 KB
Volume
22
Category
Article
ISSN
0950-9232

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โœ Mels Sluyser ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 762 KB

Recent evidence suggests that the progression to hormone resistance in some breast tumors is due to mutations in the estrogen receptor (ER). Various types of ER variants have been found in breast cancer biopsies and breast cancer cell lines. The ER variants include dominant-positive receptors that a