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Antiemetic effect of intravenous diazepam in patients receiving cis-diamminedichloroplatinum II: A pilot study

✍ Scribed by Robins, H. Ian ;Ershler, William B. ;de Jongh, Leon ;Chang, Yuang-Chi ;Drozdowicz, Paulette M. ;Carr, Brian I. ;Meyer, Deborah K.

Publisher: John Wiley and Sons
Year: 1979
Tongue: English
Weight: 203 KB
Volume: 7
Category: Article
ISSN: 0098-1532
DOI: 10.1002/mpo.2950070309

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✦ Synopsis

A pilot study suggesting the usefulness of intravenous diazepam as an antiemetic for adult patients receiving cis-diamminedichloroplatinum is presented. Observations included 24 patients and 34 courses of therapy. Patients received diazepam and prochlorperazine, and the incidence of vomiting and subjective evaluation of nausea were compared to previous courses of therapy with prochlorperazine alone. A positive response was observed in 87% of the patients. Use of other antiemetics is briefly reviewed.

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