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Antidotal effectiveness of N-acetylcysteine in reversing acetaminophen-induced hepatotoxicity: Enhancement of the proteolysis of arylated proteins

✍ Scribed by Mary K. Bruno; Steven D. Cohen; Edward A. Khairallah

Book ID
115780597
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
848 KB
Volume
37
Category
Article
ISSN
0006-2952

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## Abstract The immunosuppressive agent cyclosporine A (CsA) has been reported to exert measurable hepatotoxic effects. One of the causes leading to hepatotoxicity is thought to be reactive oxygen radical formation. The aim of this study was to investigate the effects of __N__‐acetylcysteine (NAC)