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Antidepressants may only be used as assistant therapy in cancer treatment

✍ Scribed by Da-Yong Lu; Ting-Ren Lu


Book ID
116744223
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
39 KB
Volume
70
Category
Article
ISSN
0306-9877

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## Abstract Purine and pyrimidine nucleoside analogs (NAs) are antimetabolites commonly used in cancer therapy. Administered as prodrugs, NAs permeate the mambrane using specialized transporters. Following phosphorylation, they interfere with multiple cellular pocessess inducing cytotoxicity. Toxic