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Antidepressants directly influence in situ binding of guanine nucleotide in synaptic membrane

✍ Scribed by Hiroki Ozawa; Yoshinari Katamura; Shinichi Hatta; Norihito Amemiya; Toshikazu Saito; Hideyo Ohshika; Naohiko Takahata

Book ID
118346795
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
469 KB
Volume
54
Category
Article
ISSN
0024-3205

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A novel approach for identification of adenine and guanine nucleotide-binding proteins in permeabilized cells is described. Cells were incubated for various periods with \(\alpha-{ }^{32} \mathrm{P}\)-labeled nucleotides and then briefly treated with periodate. Condensation products formed in situ b