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Antidepressant Potential of 5-HT3 Receptor Antagonist, N-n- propyl-3-ethoxyquinoxaline-2-carboxamide (6n)

✍ Scribed by Mahesh, R.; Bhatt, S.; Devadoss, T.; Jindal, A.K.; Gautam, B.K.; Pandey, D.K.

Book ID: 122653513
Publisher: Medknow Publications
Year: 2012
Tongue: English
Weight: 532 KB
Volume: 4
Category: Article
ISSN: 0975-1483
DOI: 10.4103/0975-1483.104367

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A novel series of 3-ethoxyquinoxalin-2-carboxamides were designed as per the pharmacophoric requirements of 5-HT 3 receptor antagonist using ligand-based approach. The desired carboxamides were synthesized from the key intermediate, 3-ethoxyquinoxalin-2-carboxylic acid by coupling with appropriate a