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Antidepressant-like effects of the glucocorticoid receptor antagonist RU-43044 are associated with changes in prefrontal dopamine in mouse models of depression

✍ Scribed by Yukio Ago; Shinsuke Arikawa; Miyuki Yata; Koji Yano; Michikazu Abe; Kazuhiro Takuma; Toshio Matsuda


Book ID
116785154
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
590 KB
Volume
55
Category
Article
ISSN
0028-3908

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## Abstract One hypothesis of depression is that it is caused by reduced neuronal plasticity including hippocampal neurogenesis. In this study, we compared the effects of three long‐term antidepressant treatments: escitalopram, voluntary running, and their combination on hippocampal cell proliferat