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Antidepressant effects assessed using behavior maintained under a differential-reinforcement-of-low-rate (DRL) operant schedule

โœ Scribed by James M. O'Donnell; Gerard J. Marek; Lewis S. Seiden


Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
303 KB
Volume
29
Category
Article
ISSN
0149-7634

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โœ L. S. Seiden; J. L. Dahms; R. A. Shaughnessy ๐Ÿ“‚ Article ๐Ÿ“… 1985 ๐Ÿ› Springer ๐ŸŒ English โš– 694 KB

Those antidepressant drugs that are in wide clinical use decrease response rate and increase reinforcement rate when administered to rats performing on a differential-reinforcement-of-low-rate 72-s (DRL 72-s) schedule. Drugs that are not antidepressants do not have this effect. In this experiment, t