[AAPS Advances in the Pharmaceutical Sci
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Hammarlund-Udenaes, Margareta; de Lange, Elizabeth C.M.; Thorne, Robert G.
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Article
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2013
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Springer New York
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English
⚖ 272 KB
The development of new CNS drugs is notoriously difficult. Drugs must reach CNS target sites for action and these sites are protected by a number of barriers, the most important being the blood –brain barrier (BBB). Many factors are therefore critical to consider for CNS drug delivery, e.g. active/p