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Anticonvulsant properties of some calcium antagonists on sound-induced seizures in genetically epilepsy prone rats

✍ Scribed by De Sarro, Giovambattista; De Sarro, Angelina; Federico, Francesco; Meldrum, Brian S.


Book ID
123189773
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
945 KB
Volume
21
Category
Article
ISSN
0306-3623

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## Abstract Kainic acid (KA)‐induced status epilepticus (SE) is a well‐characterized model of excitotoxic neuronal injury. Excitotoxicity results from activation of specific glutamate receptors, with resultant elevation of intracellular Ca^2+^. The CA1 and CA3 subregions of the hippocampus are espe