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Anticonvulsant activity of Aloe vera leaf extract in acute and chronic models of epilepsy in mice

โœ Scribed by Rathor, Naveen; Arora, Tarun; Manocha, Sachin; Patil, Amol N.; Mediratta, Pramod K.; Sharma, Krishna K.

Book ID
121756399
Publisher
Pharmaceutical Press
Year
2013
Tongue
English
Weight
237 KB
Volume
66
Category
Article
ISSN
2042-7158

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โœ Stuart E. Smith; Astrid G. Chapman ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 667 KB

Acute administration (0.4-12 mumol/kg, i.p.) of the NMDA antagonist D(-)CPPene (3-(2-carboxypiperazin-4-yl)propenyl-1-phosphonic acid; molecular weight = 250.2) dose-dependently reduced the incidence of sound-induced clonic seizures in genetically epilepsy-prone (GEP) rats. The ED50 value against cl