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Anticonvulsant action of SCH 23390 in the stratum of the rat

✍ Scribed by Ghada Al-Tajir; Michael S. Starr


Book ID
115885937
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
900 KB
Volume
191
Category
Article
ISSN
0014-2999

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In an attempt to understand the nature of the interactions between D1 and D2 dopamine subsystems as well as between dopamine and acetylcholine, catalepsy was assessed in rats following various drug treatments. The D1-specific antagonist SCH23390 (0.1 mg/kg) produced prompt, potent and brief (less th