During the past decade, remarkable progress has been made in the development of new drugs to treat thrombotic and cardiovascular diseases, the number one cause of mortality worldwide. In Anticoagulants, Antiplatelets, and Thrombolytics, leading experts with established records of discovery and inven
Anticoagulants, Antiplatelets, and Thrombolytics
โ Scribed by Shaker A. Mousa
- Publisher
- Humana Press
- Year
- 2010
- Tongue
- English
- Leaves
- 293
- Series
- Methods in Molecular Medicine
- Edition
- 1st Edition.
- Category
- Library
No coin nor oath required. For personal study only.
โฆ Synopsis
This practical collection provides a comprehensive update on clinically relevant in vitro and in vivo models of thrombosis and hemostasis for the discovery and testing of antithrombotics, and summarizes recent development in pharmaceuticals for the prevention and treatment of various thromboembolic disorders. Topics of the 17 contributions include low molecular weight heparins, antithrombotic drugs for the treatment of heparin-induced thrombocytopenia, guidelines for the diagnosis of deep venous thrombosis and pulmonary embolism, the development of both small and large animal models, the characteristics of factor Xa inhibitors, and the development of therapeutic candidates based on cell adhesion molecules.
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<p>During the past decade, remarkable progress has been made in the development of newer drugs to prevent and treat thromboembolic disorders, such as oral direct anti-Xa and anti-IIa antagonists, as well as oral antiplatelet ADP antagonists with rapid onset and offset. In addition, there has been co
1This collection of review articles highlights the latest development of antithrombotics and provides proven experimental methods for the further development of new and improved anticoagulants. Among the cutting-edge developments reviewed are the novel usage of low molecular weight heparins, such an
Albany College of Pharmacy, New York. Highlights the latest developments in antithrombotics and provides experimental methods for the discovery of new and improved anticoagulants. Presents relevant in vitro and in vivo models in thrombosis and hemostasis. For researchers and clinicians. DNLM: Antico