Anticancer drugs: Reversing resistance
โ Scribed by Flemming, Alexandra
- Book ID
- 109950509
- Publisher
- Nature Publishing Group
- Year
- 2008
- Tongue
- English
- Weight
- 294 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1474-1776
- DOI
- 10.1038/nrd2525
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Advances in chemotherapeutic treatment of human cancers will depend on our acquiring a real understanding of what factors limit successful therapy. One factor postulated to be important is the acquisition of a drug resistance phenotype by the patient's malignant cells. Particularly, it is thought th
## Abstract Chemotherapy has been widely used in treatment of cancer, both as systemic therapy and as part of local treatment. Unfortunately, many kinds of cancer are still refractory to chemotherapy. The anticancer drug resistance mechanisms have been extensively explored, yet have not been fully