The synthetic glucocorticoid dexamethasone is routinely used to stabilize patients with malignant gliomas. One putative target for glucocorticoid action is inducible nitric oxide synthase (iNOS), which is produced by the tumor cells as well as the host immune cells. In this study, we characterize th
Anticancer Activity of Vitamin E-Derived Compounds in Murine C6 Glioma Cells
β Scribed by Francesco Mazzini; Michele Betti; Barbara Canonico; Thomas Netscher; Francesca Luchetti; Stefano Papa; Francesco Galli
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 230 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1860-7179
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## Abstract The activity of nonspecific cholinesterase (nChE) was revealed histochemically in a small number of C6 glioma cells under conditions of spontaneous growth in culture. The nChEβpositive cells (nChE+) first appeared in 4βdayβold cultures. They occurred solitarily or in small groups with a
The cellular distribution of active and inactive transglutaminase (TGase) was studied in C6 glioma cells before and during stimulation by a serum-containing medium. The activity of the enzyme was determined in t h e soluble and insoluble fractions obtained by freezing and thawing the cells, followed
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