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Anticancer activity of artemisinin-derived trioxanes

✍ Scribed by Posner, Gary H; D’Angelo, John; M O’Neill, Paul; Mercer, Amy


Book ID
118741980
Publisher
Informa plc
Year
2006
Tongue
English
Weight
171 KB
Volume
16
Category
Article
ISSN
1354-3776

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Two sets of tricyclic 1,2,4-trioxanes containing the ABC (10, 11) and ACD ring portions (21, 22, 32, 33, 37, and 38) of artemisinin (1) were synthesized by successive photo-oxygenation of appropriate enol-ether precursors to 1,2-dioxanes and inter-and intramolecular reaction with a carbonyl compound