Antibody to acetylcholine receptor increases degradation of junctional and extrajunctional receptors in adult muscle
β Scribed by HALL, ZACH W.; WEINBERG, CRISPIN B.; REINESS, C. GARY
- Book ID
- 109709997
- Publisher
- Nature Publishing Group
- Year
- 1978
- Tongue
- English
- Weight
- 363 KB
- Volume
- 274
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/274068a0
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The rate constants for internalization and subsequent extrusion of acetylcholine receptors (AChRs) during degradation in adult innervated and denervated mouse diaphragm muscles were determined using proteinase K (PK) digestion. This procedure separated 125 I-β£-bungarotoxin (Bgt)-labeled AChRs into P
## Abstract In the studies reported here, we investigated whether the degradation of the acetylcholine receptor (AChR) in cultured muscle cells involves similar mechanisms as and is controlled in a manner similar to, the catabolism of the bulk of cell protein. We compared these processes after labe