Antibody therapy in renal cell carcinoma
β Scribed by Egbert Oosterwijk; Otto C. Boerman; Wim J. C. Oyen; Lloyd J. Old; Peter F. A. Mulders
- Publisher
- Springer-Verlag
- Year
- 2008
- Tongue
- English
- Weight
- 235 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0724-4983
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The current status of iodine 131-radiolabeled monoclonal antibody G250 (mAb G250) in renal-cell carcinoma (RCC) is described. This mAb recognizes a tumor-associated antigen that is expressed on the cell surface of almost all RCC but is not expressed on normal tissues, with the exception of gastric m
Renal call carcinoma (RCC) is the most common malignancy of the kidney in adults. Heredity appears to play a role within the etiology of RCC. Recent evidence indicates that deletions and translocations involving the short arm of chromosome 3 are important for the oncogenesis and tumor progression of