## Abstract 38โ13 is a hybridomaโproduced monoclonal rat IgM which appears to define a Burkitt's lymphomaโassociated antigen (BLA). In this paper, we describe the reactivity of 38โ13 with a panel of human haematopoietic and lymphoid cell lines. In indirect immunofluorescence (IF) assays, 15 of 26 B
โฆ LIBER โฆ
Antibody specificity and immunoglobulin VH utilization of human monoclonal CD5+ B cell lines
โ Scribed by Mieke E. M. Schutte; Saskia B. Ebeling; Karine E. Akkermans; Frits H. J. Gmelig-Meyling; Ton Logtenberg
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 751 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0014-2980
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## Abstract CD19 is an attractive therapeutic target for treating human Bโcell tumors. In our study, chimeric (c) divalent (cHD37) and tetravalent (cHD37โDcVV) antiโCD19 monoclonal antibodies (MAbs) were constructed, expressed and evaluated for their binding to human 19โpositive (CD19^+^) tumor cel