Human papillomaviruses (HPVs) are strongly associated with the development of high grade cervical intraepithelial neoplasia (CIN) and cervical carcinoma, with between 40-80% of patients with cervical carcinoma being attributed to a single HPV type, HPV16 depending on the methods used and geographica
Antibody responses to HPV16 virus-like particles in women with cervical intraepithelial neoplasia infected with a variant HPV16
โ Scribed by JRM Ellis; I Etherington; D Galloway; D Luesley; LS Young
- Book ID
- 119503359
- Publisher
- The Lancet
- Year
- 1997
- Tongue
- English
- Weight
- 31 KB
- Volume
- 349
- Category
- Article
- ISSN
- 0140-6736
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## Abstract The impact of a human papillomavirus (HPV) vaccine on development of cervical intraepithelial neoplasia grade 2โ3 or adenocarcinoma __in situ__ (CIN2โ3/AIS) in women with ongoing HPV16 or 18 infections prevaccination is reported. Seventeen thousand sixโhundred and twentyโtwo women aged
## Abstract Persistent infection with human papillomaviruses (HPV) is a prerequisite for the development of cervical cancer. Vaccination with virusโlike particles (VLP) has demonstrated efficacy in prophylaxis but lacks therapeutic potential. HPV16 L1E7 chimeric virusโlike particles (CVLP) consist
Sera from patients with cervical cancer, cervical intraepithelial neoplasia (CIN) and non-genital cancers, and from healthy individuals, were investigated for antibodies to human papilloma virus (HPV) early proteins E4, E6 and E7 and the major capsid protein LI by Western blot analysis of recombinan