𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Antibody responses to herpesvirus papio antigens in baboons with lymphoma

✍ Scribed by Russell H. Neubauer; Harvey Rabin; Bruce C. Strnad; Boris A. Lapin; Lelita A. Yakovleva; Eleonor Indzie

Publisher
John Wiley and Sons
Year
1979
Tongue
French
Weight
633 KB
Volume
23
Category
Article
ISSN
0020-7136

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✦ Synopsis

Abstract

An Epstein‐Barr virus‐related herpesvirus, termed Herpesvirus papio (HVP), was isolated from baboons (Papio hamadryas) at the Institute of Experimental Pathology and Therapy, Sukhumi, USSR, where there is a continuing outbreak of lymphoma. In the present study sera from diseased baboons and from age‐and sex‐matched control animals were examined for antibodies to HVP antigens. Results showed that animals with lymphoid disease had antibodies to HVP virus capsid, early, soluble, and nuclear antigens at higher frequencies and at higher titers than did control animals. Antibody titers were nat age‐or sex‐related. No concordancy was detected for antibodies to soluble and nuclear antigens. The sera were also examined for antibodies to two other widely distributed viruses of hamadryas baboons, cytomegalovirus and foamy virus. The results of these studies did nat indicate a disease‐related role for either of these viruses.

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