Antibody responses of mice exposed to low-power microwaves under combined, pulse-and-amplitude modulation
✍ Scribed by Dr. B. Veyret; C. Bouthet; P. Deschaux; R. de Seze; M. Geffard; J. Joussot-Dubien; M. le Diraison; J.-M. Moreau; A. Caristan
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 612 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0197-8462
No coin nor oath required. For personal study only.
✦ Synopsis
Irradiation by pulsed microwaves (9.4 GHz, 1 ps pulses at 1 ,OOO/s), both with and without concurrent amplitude modulation (AM) by a sinusoid at discrete frequencies between 14 and 41 MHz, was assessed for effects on the immune system of Balb/C mice. The mice were immunized either by sheep red blood cells (SRBC) or by glutaric-anhydride conjugated bovine serum albumin (GA-BSA), then exposed to the microwaves at a low rms power density (30 pW/cm2; whole-body-averaged SAR -0.015 W/kg). Sham exposure or microwave irradiation took place during each of five contiguous days, 10 h/day. The antibody response was evaluated by the plaque-forming cell assay (SRBC experiment) or by the titration of IgM and IgG antibodies (GA-BSA experiment). In the absence of AM, the pulsed field did not greatly alter immune responsiveness. In contrast, exposure to the field under the combined-modulation condition resulted in significant, AM-frequency-dependent augmentation or weakening of immune responses.