ANTIBODY RESPONSE TO PRE-S2 AND HEPATITIS B VIRUS INDUCED LIVER DAMAGE
β Scribed by Alberti, Alfredo; Pontisso, Patrizia; Tagariello, Giuseppe; Cavalletto, Daniela; Chemello, Liliana; Belussi, Fabio
- Book ID
- 123030891
- Publisher
- The Lancet
- Year
- 1988
- Tongue
- English
- Weight
- 590 KB
- Volume
- 331
- Category
- Article
- ISSN
- 0140-6736
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A hybrid cell line producing monoclonal antibodies recognizing an epitope encoded by the pre-(S)2 region of hepatitis B virus (HBV) genome was obtained by fusion of mouse myeloma cells with lymphocytes from mice immunized with HBV. The monoclonal antibody Mo-Fl24 secreted from the hybrid line reacte
## Abstract PreβS proteins may have an important role in virus assembly and virus entry into the host cell. The presence of preβS proteins in serum has also been thought to correlate with active viral replication. To investigate whether preβS proteins in serum might have additional diagnostic and/o