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Antibody recognition of a conformational epitope in a peptide antigen: Fv-peptide complex of an antibody fragment specific for the mutant EGF receptor, EGFRvIII

✍ Scribed by Roxanne C Landry; Alex C Klimowicz; Sylvie J Lavictoire; Svetlana Borisova; Dayantha T Kottachchi; Ian A.J Lorimer; Stephen V Evans


Book ID
115631005
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
434 KB
Volume
308
Category
Article
ISSN
0022-2836

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Solution conformation of an immunogenic
✍ M. AntΓ²nia Molins; Miquel Γ€ngel Contreras; Ignacio Fita; Miquel Pons πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 175 KB πŸ‘ 2 views

The conformation of a [15]-peptide (H-VKAETRLNPDLQPTE-NH 2 ) from VP2 of rhinovirus HRV2 complexed with a Fab fragment was previously shown by X-ray crystallographic studies to be similar to the one found in the corresponding region of HRV1A. Antibodies raised against this peptide bind to and neutra