Antibody Persistence and Immune Memory 4 Years Post-Vaccination With Combined Hepatitis A and B Vaccine in Adults Aged Over 40 Years
β Scribed by Roman Chlibek; Frank von Sonnenburg; Pierre Van Damme; Jan Smetana; Petr Tichy; Bhavyashree Gunapalaiah; Maarten Leyssen; Jeanne-Marie Jacquet
- Book ID
- 111280166
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 558 KB
- Volume
- 18
- Category
- Article
- ISSN
- 1195-1982
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## Abstract A combined hepatitis A and B vaccine is available since 1996. Two separate openβlabel primary studies evaluated the immunogenicity and safety of this hepatitis A and B vaccine (720βEI.U of HAV and 20βΒ΅g of HBsAg) in 306 healthy subjects aged 17β43 years who received three doses of the v
## Abstract Longβterm persistence of vaccineβinduced immune response in adults was assessed annually for 15 years following primary immunization with a twoβdose inactivated hepatitis A vaccine. In 1992, 119 and 194 subjects aged 17β40 years and naΓ―ve for hepatitis A virus (HAV) were enrolled in two